Nothing important IMO. I don’t think the Neo can do ERG mode power smoothing, but I’m not a fan of that feature. The main benefit of the Core is price, and the Neo firmware update to enable virtual shifting has not been out for very long so I don’t have high confidence that any bugs in it are well understood yet.
No. None of the automatic incline products like the Alpine are compatible with the Ride.
If you haven’t read the topic about the new firmware, I recommend it: