Some more observations: Also happens with latest Windows 11 Insider Build (22000.282), Non-WHQL-Radeon-Software-Adrenalin-2020-21.11.1-Win10-Win11-64Bit-Nov3 and ANT+.
So no BT issue. Crashed almost immediately after entering Watopia. Switched then back to Bluetooth, did a 15min ride in Yorkshire with no issues.
For me its Windows 11 with any Radeon driver released for Windows 11 and riding in Watopia when the crashed happen. Haven’t tried any other worlds beside Yorkshire, where the game seems to run fine.
Also reported the error to AMD, but no feedback yet.